pentobarbital will reduce the extent or impact of fosamprenavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital decreases amounts of panobinostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Robust CYP3A4 inducers can minimize panobinostat degrees by ~70% and bring about treatment failure.
pentobarbital will minimize the level or influence of pazopanib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
Keep an eye on Closely (one)pentobarbital will decrease the extent or effect of hydrocodone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Caution when discontinuing CYP3A4 inducers which are coadministered with hydrocodone; plasma concentrations of hydrocodone may possibly improve and may result in possibly deadly respiratory depressionSerious - Use Alternative (1)hydrocodone, pentobarbital.
pentobarbital will decrease the extent or effect of quetiapine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will lower the extent or impact of fosphenytoin by impacting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Keep an eye on.
pentobarbital raises toxicity of ifosfamide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. CYP3A4 inducers may possibly increase the metabolism of ifosfamide to its Energetic alkylating metabolites.
pentobarbital will lower the level or influence of zaleplon by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unknown.
pentobarbital will lessen the level or outcome of artemether/lumefantrine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration with solid CYP3A4 inducers may end up in decreased serum concentrations and lack of antimalarial efficacy
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Critical heart symptoms involve quickly or pounding heartbeats, fluttering in your upper body, shortness of breath, and unexpected dizziness;
pentobarbital will minimize the extent website or effect of clozapine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Check Intently (3)pentobarbital will lessen the level or influence of diazepam intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Robust or average CYP3A4 inducers might raise rate of diazepam elimination; for that reason, efficacy of diazepam may be lowered.
pentobarbital will lower the level or impact of indinavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.